Michael Jackson's Ghost Spooks Propofol Maker Teva

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Offline willddoMJ

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Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 20, 2011, 07:46:01 AM
Michael Jackson's Ghost Spooks Propofol Maker Teva

The worldwide scorn directed at those closest to Michael Jackson in his final days may have extended to the drug Propofol and its Irvine-based maker, which announced it is laying off 200 employees this year after having already let go 70 workers.

Teva Pharmaceuticals maintains it already discontinued the hypnotic drug--not because of Jackson's death, but because Propofol was hard to manufacture, the company got little or no profit from it and there were pending lawsuits tied to it.


​Risks from the nonmedical use of Propofol were greatly exposed when the Los Angeles County coroner concluded in August 2009 that the King of Pop died from a mixture of Propofol--nicknamed "Milk of Amnesia"--and the benzodiazepine drug Lorazepam. Ten bottles of Propofol were found in Jackson's home.

Propofol and Teva, which is headquartered in Israel, have had a rocky relationship. The company previously halted production and recalled some Propofol in 2009 after 41 patients fell ill with flu-like symptoms. That fueled several of the lawsuits.

Teva announced it will kill 195 of its Irvine jobs by Feb. 6, according to an Orange County Register report.

"Our Irvine, California, facility has been under a voluntary manufacturing and distribution hold since April 2010," said Denise Bradley, Teva spokeswoman in a company statement. "Prior to this reduction, we have not laid off any employees as a result of this voluntary production hold. The jobs that are being eliminated are all various production jobs and support staff at the facility."'

They should moonwalk out to their cars.


http://http://blogs.ocweekly.com/navelgazing/2011/01/michael_jackson_propofol_teva.php
« Last Edit: December 31, 1969, 07:00:00 PM by Guest »
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Offline Sinderella

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 20, 2011, 08:25:29 AM
Interesting!!

Definitley worth looking into more.
I recall Fleak at the prelim saying she -at the time in 09- had no idea what propofol was,and tbh I don't think the rest of the world did either.There have only been a handful of deaths related back to an overdose/misusage of this drug,if that..I think it is about 2/3 people and that was down to self injecting and one case was due to intoxication from 100+injections of the liquid.
There is little to nothing really known about propofol before this happened.I had never heard of it and had to google the effects when Michael 'died' from it so I wonder what these numerous 'pending law suits' are against the company.
I can see several where from people getting the flu or something from it but other than that...what other law suits could be tied to it?
« Last Edit: December 31, 1969, 07:00:00 PM by Guest »

Offline MissG

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 20, 2011, 08:47:47 AM
Quote from: "willddoMJ"
Michael Jackson's Ghost Spooks Propofol Maker Teva

The worldwide scorn directed at those closest to Michael Jackson in his final days may have extended to the drug Propofol and its Irvine-based maker, which announced it is laying off 200 employees this year after having already let go 70 workers.

Teva Pharmaceuticals maintains it already discontinued the hypnotic drug--not because of Jackson's death, but because Propofol was hard to manufacture, the company got little or no profit from it and there were pending lawsuits tied to it.


​Risks from the nonmedical use of Propofol were greatly exposed when the Los Angeles County coroner concluded in August 2009 that the King of Pop died from a mixture of Propofol--nicknamed "Milk of Amnesia"--and the benzodiazepine drug Lorazepam. Ten bottles of Propofol were found in Jackson's home.

Propofol and Teva, which is headquartered in Israel, have had a rocky relationship. The company previously halted production and recalled some Propofol in 2009 after 41 patients fell ill with flu-like symptoms. That fueled several of the lawsuits.

Teva announced it will kill 195 of its Irvine jobs by Feb. 6, according to an Orange County Register report.

"Our Irvine, California, facility has been under a voluntary manufacturing and distribution hold since April 2010," said Denise Bradley, Teva spokeswoman in a company statement. "Prior to this reduction, we have not laid off any employees as a result of this voluntary production hold. The jobs that are being eliminated are all various production jobs and support staff at the facility."'

They should moonwalk out to their cars.



http://http://blogs.ocweekly.com/navelgazing/2011/01/michael_jackson_propofol_teva.php
Don´t know if can be useful. Here it goes.
Heart Attack Victim Moved for Michael Jackson
http://abcnews.go.com/GMA/MichaelJackso ... ?id=529513
(Page Unavailable  :roll: )
Feb. 25, 2005
A woman who had suffered a massive heart attack died after hospital personnel moved her out of a trauma room to accommodate a flu-stricken Michael Jackson, the patient's family said.

Jury selection in Jackson's child molestation child had to be temporarily postponed Feb. 15 when the pop star was taken to Marian Medical Center in Santa Maria, Calif., complaining of flu-like symptoms. Manuela Gomez Ruiz, a 74-year-old grandmother, was moved from the primary trauma room and taken off the machine ventilator, with her breathing instead assisted manually by hand pump, until she was relocated to a smaller room nearby, her family told ABC News.
http://forums.cnet.com/7723-6130_102-88624.html
« Last Edit: December 31, 1969, 07:00:00 PM by Guest »
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Offline nefari

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 20, 2011, 09:55:18 AM
I had Propofol numerous times before 2009 and the one thing that stands out to me is every time I am laying on the table waiting on them to hook me up, I get asked over and over about old injuries that could start to bleed out. They stress to me that Propofol can cause old injuries to bleed and it seems to be a big concern. This always made me a bit nervous even though I've been under at least 6 times with Propofol.
« Last Edit: December 31, 1969, 07:00:00 PM by Guest »
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Offline mjfjei7777

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 22, 2011, 01:39:21 PM
nefari
 what kind of operationa did you have that you had to take this drug propofol?
i never heard of it untill this thing with michael .
hugs
mjfjei7777
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Offline Sinderella

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 22, 2011, 02:47:59 PM
Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.
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Offline Grace

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 22, 2011, 03:04:56 PM
I'm adding a post from another thread.
Quote from: "Grace"
Mid July 2009 the first recalls of Propofol were published by the FDA for safety reasons (bacterial contamination of the product). The timing is not astonishing - the name of Propofol was in all newspapers after Michael's "passing". However:
Quote
A Teva spokeswoman said the company had been contacted by the Drug Enforcement Administration about a lot number on a specific propofol vial "in relation to an investigation they are conducting," which she did not confirm or deny involved the Jackson death.

That lot number, she said, is not one of those involved in the recall.
http://http://www.medpagetoday.com/ProductAlert/Prescriptions/15134

Quote
More than 57,000 vials of Teva-manufactured propofol were recalled after the U.S. Centers for Disease Control and Prevention (CDC) issued a health advisory on July 13, 2009, warning physicians not to use 100 ml vials of propofol from two lots.

One of main manufacturers of Propofol is TEVA, another is Hospira.
Teva received a warning from FDA in April 2010 after they had to recall 100 ml vials from the market:
Quote
Teva Pharmaceuticals failed to have proper quality control measures in place to prevent bacterial contamination from entering batches of their generic version of the anesthetic propofol, leading to a recall last year after at least 40 people became ill, according to federal inspectors.
http://http://www.aboutlawsuits.com/teva-propofol-warning-letter-9927/

Teva stopped production thus resulting in a product shortage in the U.S.
Quote
The Teva propofol recall, and another propofol recall by Hospira, Inc. due to particulate matter contamination in November, has caused a shortage of propofol in the United States. As a result, the FDA has given APP Pharmaceuticals Inc. permission to import Propoven, a similar drug, into the U.S. Propoven has not been approved by FDA, but is in use in a number of other countries around the world.
http://http://www.aboutlawsuits.com/teva-propofol-warning-letter-9927/

Where do the contaminations result from?

Quote
The  drug  is available  as  an  aqueous  lipid   emulsion  
(Dipdvan|      ICI   Pharmaceuticals)
containing   I%  propofol,   10%  soyabean  oil,   1.2%  egg
phosphatide  and  2.25% glycerol.
Product  information  provided with propofol states that
the  preparation  should  be  "...  drawn  aseptically  into  a
sterile syringe  ...  immediately alter opening the ampoule"
and  that  it should  be injected "...  without  delay." Despite
these  recommendations,   it  is  often  difficult  in  clinical
practice to ensure that there is no delay between drawing-
up  and  administration.  Therefore  propofol  can  often  be
left  standing  in  a  sterile  syring~  for  some  period  of time
prior to administration.  
http://http://www.springerlink.com/content/k60121887j07mr03/

Quote
The intravenous anaesthetic propofol may become contaminated once the ampoules have been opened. [...] When propofol is stored in opened ampoules, the bacterial contamination rate is high.
http://http://www.ingentaconnect.com/content/gmed/eja/2002/00000019/00000006/art00010

Quote
Propofol can support rapid microbial growth and endotoxin production. To avoid infectious complications, scrupulous aseptic technique should be used when preparing or administering this anesthetic.
http://http://www.jstor.org/pss/30145228

FDA issued a warning about proper handling in 2007 already.
http://http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm125817.htm

Quote
Escherichia coli is one of the most frequent causes of many common bacterial infections, including cholecystitis, bacteremia, cholangitis, urinary tract infection (UTI), and traveler's diarrhea, and other clinical infections such as neonatal meningitis and pneumonia.

Drawing out a case that has not yet been subject to interest:
We face three sources of contamination of the product with bacteria:
1) the fact that the product is containing soy bean oil which as a lipid supports bacteria growth
2) improper manufacturing
3) improper handling at anesthesia administration in divergence to guidelines


Quote
Therefore  propofol  can  often  be
left  standing  in  a  sterile  syring~  for  some  period  of time
prior to administration.  For some anaesthetists,  this delay
is  on  occassion  deliberate  with  several  induction  doses
prepared  in  advance  for  an  operating  list.  The  problem
of  clinical  practicalities  occasionally  resulting  in  diver-
gence from package  insert  guidelines  has  been previously
identified,  l but not  quantified.
http://http://www.springerlink.com/content/k60121887j07mr03/
http://http://michaeljacksonhoaxforum.com/phpbb2/viewtopic.php?f=217&t=17015&p=292529#p292529

Quote
Hospira Issues Second Drug Recall in 6 Months on FDA Warning
-Bloomberg
04/16/2010 - Hospira Inc. recalled two drugs for the second time in six months because of manufacturing defects that prompted an April 12 warning letter from the U.S. Food and Drug Administration, said Dan Rosenberg, a company spokesman. The drugs -- Propofol, an anesthetic agent, and Liposyn, an intravenous nutritional product -- were recalled on April 1, Rosenberg said. The company told the FDA the products had been contaminated by particulates during the manufacturing process, he said. The drugs are sold to hospitals and doctors. More>>>


Teva Pharmaceuticals USA issues a voluntary nationwide recall of Propofol Injectable Emulsion

-FDA
12/17/2009 - In July of 2009 Teva Pharmaceuticals USA initiated a voluntary recall of Propofol Injectable Emulsion 10 mg/mL 100 mL vials, lot numbers 31305429B and 31305430B. The product lots identified are being recalled due to the presence of elevated endotoxin levels in some vials within these lot numbers. More>>>

Hospira Brand Propofol and Liposyn Products - Recall
-FDA
11/11/2009 - Hospira, Inc.and FDA notified healthcare professionals of the recall of 85 lots of Liposyn II 10%, Liposyn II 20%, Liposyn III 10%, Liposyn III 20%, and Liposyn III 30%, and 73 lots of Propofol Injectable Emulsion 1% products that begin with the lot numbers 79 and 80 because some of the containers may contain particulate matter. The source of the particulate matter has been identified as stainless steel equipment used in the manufacturing process. More>>>

Hospira Issues Nationwide Voluntary Recall of Certain Lots of Liposyn and Propofol Products That May Contain Particulate Matter
-Pharmaceutical Processing
11/12/2009 - Hospira, Inc., a global specialty pharmaceutical and medication delivery company, is voluntarily recalling 85 lots of Liposyn™ II 10%, Liposyn II 20%, Liposyn III 10%, Liposyn III 20%, Liposyn III 30% and 73 lots of Propofol Injectable Emulsion 1% products that begin with the lot numbers 79 and 80 because some of the containers may contain particulate matter. More>>>

If you or a loved one have suffered injury or loss as a result of contaminated Propofol or Liposyn you may be entitled to compensation. Contact The Propofol Lawyers of Ennis & Ennis, P.A. today for a free case evaluation by filling out the form on this page or calling toll-free 1-800-856-6405.
http://http://www.ennislaw.com/propofol_liposyn_recall_news_archive.html
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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 22, 2011, 04:13:51 PM
Quote from: "Sinderella"
Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.
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Offline Sinderella

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 22, 2011, 04:55:50 PM
Quote from: "~Souza~"
Quote from: "Sinderella"
Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.

Well she is a non believer,she might have been lying to prove the whole Michael died at the hands of Murray BS,i'm just trying to find the note on fb now.LIKELY.
I'm allergic to anaesthetic and have to be strapped down because I fit/fight the surgeons and take my socks and heart monitor's off and all kinds haha!I end up in a room on my own.
I might ask for prop fool for this knee surgery I have to have soon and report back on my reactions,i'll tell them it's all the rage in Holland
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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 22, 2011, 05:12:23 PM
Quote from: "Sinderella"
Quote from: "~Souza~"
Quote from: "Sinderella"
Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.

Well she is a non believer,she might have been lying to prove the whole Michael died at the hands of Murray BS,i'm just trying to find the note on fb now.LIKELY.
I'm allergic to anaesthetic and have to be strapped down because I fit/fight the surgeons and take my socks and heart monitor's off and all kinds haha!I end up in a room on my own.
I might ask for prop fool for this knee surgery I have to have soon and report back on my reactions,i'll tell them it's all the rage in Holland

The room with those big cushions attached to the walls you mean? :lol:
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Offline Sinderella

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 22, 2011, 06:35:25 PM
Hell yeah!Don't be fooled,they are really comfy and if you have a pack of sharpies,you can decorate it how you want
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Offline reading_on

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 24, 2011, 06:00:18 AM
Quote from: "~Souza~"
Quote from: "Sinderella"
Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.

 Yea Souza, I think there are a couple of ways they give it and one of them the patient gets a shot of something else first (don't know what that is) and then Propofol will maintain the anesthesia. The other is straight dosing,(which my son had to maintain his coma longer to heal his brain, and yep, soon as it came off after days on it he was wide awake in what seemed like seconds.
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Offline Sinderella

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 27, 2011, 04:07:59 PM
If I can find where she wrote it I will post it up here.

Non's.....pfftt...what can you do..
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Offline MJonmind

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Re: Michael Jackson's Ghost Spooks Propofol Maker Teva

  • on: January 27, 2011, 11:57:50 PM
Quote from: "reading_on"
Yea Souza, I think there are a couple of ways they give it and one of them the patient gets a shot of something else first (don't know what that is) and then Propofol will maintain the anesthesia. The other is straight dosing,(which my son had to maintain his coma longer to heal his brain, and yep, soon as it came off after days on it he was wide awake in what seemed like seconds.
I'm sad to hear your son had to go through an ordeal. How's he doing now?
« Last Edit: December 31, 1969, 07:00:00 PM by Guest »